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Ebola survivors donate plasma to tackle outbreak

EUREKALERT                                                                           April 22, 2015
UNIVERSITY OF LIVERPOOL -- 
The first donations of plasma, from survivors of the Ebola epidemic in Sierra Leone, have been received by an international research team working to help tackle current and future disease outbreaks in West Africa.

The team, led by scientists at the University of Liverpool and colleagues at the College of Medicine and Allied Health Services, Ministry of Health, Sierra Leone, is investigating how plasma from Ebola survivors could help treat patients with the disease at the Ebola Treatment Unit, run by the 34th Regiment Military Hospital group in Freetown.

Dr Calum Semple, from the University's Institute of Child Health, and his collaborators developed a convalescent plasma protocol in readiness for an outbreak, such as Ebola, as part of the outbreak preparatory work of the International Severe Acute Respiratory and Emerging Infection Consortium.

The study is one of several being supported by the Wellcome Trust's platform for evaluating experimental Ebola therapeutics in West Africa.

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http://www.eurekalert.org/pub_releases/2015-04/uol-esd042215.php

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Scientists to share real-time genetic data on deadly MERS, Ebola

REUTERS by Kate Kelland                     April 21, 2015

LONDON, April 21 - Genetic sequence data on two of the deadliest yet most poorly understood viruses are to be made available to researchers worldwide in real time as scientists seek to speed up understanding of Ebola and MERS infections.

The project, led by British scientists with West African and Saudi Arabian collaboration, hopes to encourage laboratories around the world to use the live data -- updated as new cases emerge -- to find new ways to diagnose and treat the killer diseases, and ideally, ultimately, prevent them.

"The collective expertise of the world's infectious disease experts is more powerful than any single lab, and the best way of tapping into this...is to make data freely available as soon as possible," said Jeremy Farrar, director of the Wellcome Trust global health charity which is funding the work.

The gene sequences, already available for MERS cases and soon to come in the case of Ebola, will be posted on the website virological.org for anyone to see, access and use.

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http://af.reuters.com/article/topNews/idAFKBN0NC19W20150421?sp=true

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Ebola rapid diagnostic kit developed by UK scientists in Sierra Leone

Doctors says the kit, if approved by health authorities, could transform the admissions process with its capacity to deliver results within 20 minutes

THE GUARDIAN    by Lisa O'Carroll                              March 29, 2015

A rapid Ebola diagnostic kit similar to a pregnancy kit has been developed by British military scientists and NHS medics in Sierra Leone.

Health care workers prepare to entering a high risk zone at an Ebola virus clinic in Sierra Leone, where the diagnostic kit has been undergoing tests. Photograph: Michael Duff/AP

It can be administered at the bedside and return its first results within 20 minutes, slashing dramatically the normal 24-hour turnaround for lab results.

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3 pitfalls Ebola recovery must avoid

DEVEX   by Molly Anders                                                                                         Feb. 19, 2015

...While the Ebola crisis is far from over, officials in government and the international development community have begun to think more the medium and long term. What can they learn from past post-crisis recovery initiatives?

  Health worker Alivin Davis poses next to the a board featuring handprints of Ebola survivors in Liberia. Photo by: Neil Brandvold / USAID / CC BY-NC

Devex asked aid officials and government officials from the region how to avoid some of the most common pitfalls that can plague — haunt, even — recovery and reconstruction efforts. Here are three of them.

1. Quality over quantity.

....By not paying closer attention to the economic effects of foreign aid on the local market, humanitarian groups hurt livelihoods and slowed reconstruction in the country.

2. Prioritize local ownership....

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IMF to provide new funds to help three main Ebola-hit nations

REUTERS   by James Harding Giahyue                                                  Jan. 8, 2015

The International Monetary Fund is preparing around $150 million in additional support to Liberia, Sierra Leone and Guinea, the countries at the heart of the Ebola epidemic, the Fund's representative in Liberia told Reuters on Thursday.

"In Guinea and Sierra Leone, existing Fund financial programs are being augmented to provide more resources to these countries. In Liberia, a one-off disbursement under the Fund's Rapid Credit Facility is being considered," Charles Amo-Yartey told Reuters in an email.

The money could be made available in the first quarter of this year and would add to $130 million disbursed by the Fund in September.

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http://www.reuters.com/article/2015/01/08/health-ebola-imf-idUSL6N0UN3RA20150108

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J&J, Bavarian Nordic start clinical tests in Ebola vaccine race

REUTERS     by Ben Hirschler                              Jan. 6, 2015
LONDON --Johnson & Johnson has started clinical trials of its experimental Ebola vaccine, which uses a booster from Denmark's Bavarian Nordic, making it the third such shot to enter human testing.

The initiation of the Phase I study in Britain, which had been expected about now, marks further progress in the race to develop a vaccine against a disease that has killed more than 8,000 people in West Africa since last year.

Two other experimental vaccines, one from GlaxoSmithKline and a rival from NewLink and Merck, are already in clinical development. However, the J&J vaccine offers a different approach, since it involves two separate injections.

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http://www.reuters.com/article/2015/01/06/us-health-ebola-vaccine-j-j-idUSKBN0KF0HH20150106

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First British volunteers fly to Sierra Leone to battle Ebola

THE ASSOCIATED PRESS                                Nov. 22, 2014

FREETOWN, Sierra Leone -- The first wave of volunteers from Britain's National Health Service arrived in Sierra Leone Saturday amid what the World Health Organization has described as an "intense" surge in cases.

A sign reading 'Kill Ebola Before Ebola Kill You', on a gate is mounted as part of the country's Ebola awareness campaign in the city of Freetown, Sierra Leone, Sept. 14, 2014. (AP / Michael Duff, File)

More than 30 NHS staffers, including general practitioners and nurses, were expected to stay in Freetown, the capital, for one week of training before moving to treatment centres across the country, Britain's Department for International Development said in a statement.

They join nearly 1,000 British soldiers, scientists and aid workers already in the country participating in the Ebola fight, International Development Secretary Justine Greening said.

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Ebola outbreak: UK aid ship docks in Sierra Leone

The Argus arrives with supplies and medical personnel to assist Serra Leone

 BBC                                                              Oct. 30, 2010

By AndrewHarding

FREETOWN, Sierra Leone--  A British Navy support ship ship has arrived in Sierra Leone to help deal with the deadly Ebola outbreak in the West African country.

Royal Fleet Auxiliary Argus is carrying food, medical equipment, three helicipeters and 32 pick-up trucks, to help keep hard-pressed Ebola treatment centres going.

Doctors, nurses and military personnel are also on board.

The BBC's Africa correspondent Andrew Harding said it would act as an offshore base for the aid effort. and described it as an "important moment".

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http://www.bbc.com/news/uk-29836657

 
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WHO says Ebola vaccine plans accelerating as trials advance

WHO ANNOUNCES  EBOLA VACCINE TRIALS WILL BE SPEEDED UP TO DECEMBER.
THREE RELATED STORIES.   (Scroll down)

REUTERS                                       OCT. 24

By Stephanie Nebehay and Kate Kelland

GENEVA/LONDON, Oct 24 (Reuters) - Trials of Ebola vaccines could begin in West Africa in December, a month earlier than expected, and hundreds of thousands of doses should be available for use by the middle of next year, the World Health Organization said on Friday.

Vaccines are being developed and made ready in record time by drugmakers working with regulators, the U.N. health agency said, but questions remain about their safety and efficacy which can only be settled by full clinical trials.

"Vaccine is not a magic bullet, but when ready they may be a good part of the effort to turn the tide against the epidemic," senior WHO official Marie-Paule Kieny told a news briefing after a meeting in Geneva of industry executives, global health experts, drug regulators and funders.

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UK to introduce Ebola screening as death of Briton reported in Macedonia

THE GUARDIAN                         Oct. 9, 2014

By Robert Booth

London --Travellers arriving at Heathrow and Gatwick airports from west Africa are to be screened for symptoms of Ebola, Downing Street announced on Thursday night after a day of confusion over the government’s response to the virus that has claimed more than 3,800 lives.

People travelling from the worst-affected countries – Liberia, Sierra Leone and Guinea – will face a questionnaire about their recent travel history, who they have been in contact with and their onward travel arrangements.

 People travelling from Liberia, Sierra Leone and Guinea will be screened for Ebola symptoms.Photograph: Oli Scarff/Getty  Images

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